TY - JOUR
AB - Reactions 2064, p80 - 21 Jun 2025 Elevated liver enzymes: case report A 23-year-old man developed elevated liver enzymes during treatment with bleomycin, cisplatin and etoposide for testicular cancer [routes and dosages not stated]. The man with a history of deep vein thrombosis (DVT) involving the inferior vena cava (IVC) and bilateral iliac veins managed with long-term unspecified anticoagulation presented to the emergency department with diffuse abdominal pain and progressive right testicular mass. He was haemodynamically stable but reported exertional dyspnoea consistent with New York Heart Association (NYHA) functional class II and intermittent febrile episodes. Further imaging testing revealed an enlarged right testis with intratesticular calcifications and a heterogeneous, hypervascular mass. Based on these findings, he was diagnosed with testicular cancer. Given the suspicion of malignancy, his testicular mass was successfully excised without perioperative complications. Findings of the chest and abdomen revealed extensive metastases to both lungs, retroperitoneal lymph nodes, and liver. An irregular mass was also identified extending from the inferior vena cava into the right atrium. Three days post-surgery, he was started on chemotherapy with bleomycin, etoposide, and cisplatin (BEP regimen). However, he developed significant elevation in liver enzymes secondary to bleomycin, etoposide and cisplatin. His AST 
TI - Bleomycin/Cisplatin/Etoposide
JO - Reactions Weekly
DO - 10.1007/s40278-025-84344-0
DA - 2025-06-01
UR - https://www.deepdyve.com/lp/springer-journals/bleomycin-cisplatin-etoposide-J4R0GZTV2e
SP - 80
EP - 80
VL - 2064
IS - 1
DP - DeepDyve
ER -