TY - JOUR AU - Perales, Miguel-Angel AB - EDIT ORIAL C OMMENTAR Y Adenovirus Viremia and Infection After Reduced-Intensity Allogeneic Hematopoietic Stem Cell Transplant: Should We Institute a Routine Screening Program? Gabriela Soriano and Miguel-Angel Perales Adult Bone Marrow Transplantation Service, Department of Medicine, Memorial Sloan-Kettering Cancer Center, and Weill Cornell Medical College, New York, New York (See the Major Article by Sive et al, on pages 1362–70.) Adenovirus (ADV) has been identified can predict viremia and outcomes? (4) reported incidence was 19.7% with a 3% as an important cause of morbidity and Can these risk factors be mitigated? (5) mortality rate [4]. Several other small mortality after allogeneic hematopoietic Are there effective treatments and has studies have reported an incidence of stem cell transplantation (HSCT) [1–8]. early treatment been shown to affect about 5% when routine screening with Polymerase chain reaction (PCR)–based outcome? blood PCR was performed [9, 10]. A assays now allow rapid quantification of The reported incidence of ADV recent large retrospective review report- ADV load in the blood. However, unlike viremia and associated morbidity and ed a similar 5% incidence in 539 pa- cytomegalovirus (CMV), for which pre- mortality vary widely in the literature. tients tested for ADV by PCR [8]. emptive therapy TI - Editorial Commentary: Adenovirus Viremia and Infection After Reduced-Intensity Allogeneic Hematopoietic Stem Cell Transplant: Should We Institute a Routine Screening Program? JO - Clinical Infectious Diseases DO - 10.1093/cid/cis695 DA - 2012-11-15 UR - https://www.deepdyve.com/lp/oxford-university-press/editorial-commentary-adenovirus-viremia-and-infection-after-reduced-InySVVQ7Vw SP - 1371 EP - 1372 VL - 55 IS - 10 DP - DeepDyve ER -