TY - JOUR
AU - Gillis, David
AB - PAGE 37 / FEBRUARY 2002 Chemotherapy Foundation Symposium Antisense Agents Effectively Induce Apoptosis in Prostate & Hematologic Cancers By David Gillis compounds directed to inhibit bcl-2. nous leukemia (AML), the combina- Animal studies have shown that t i o n o f g e m t u z u m a b o z o g a m i c i n E W Y O R K C I T Y — T h e a n t i - Genasense plus docetaxel-treated mice (Mylotarg) and antisense substantial- sense agent Genasense (former- with the prostate cancer PC3 tumor line ly increased the induction of apopto- ly known as G-3139) may offer survived beyond 60 days (long term). sis over gemtuzumab ozogamicin N a promising new approach for No long-term survivors were found in alone. the treatment of hormone-refractory the other treatment regimens groups— Chronic lymphocytic leukemia prostate cancer, according to data pre- saline control, Genasense alone, and ( C L L ) c e l l s s h o w a s u b s t a n t i a l sented here at the most recent Chemo- docetaxel alone. decrease in viability when exposed to 
TI - Antisense Agents Effectively Induce Apoptosis in Prostate & Hematologic Cancers
JO - Oncology Times
DO - 10.1097/01.COT.0000294263.71367.35
DA - 2002-02-01
UR - https://www.deepdyve.com/lp/wolters-kluwer-health/antisense-agents-effectively-induce-apoptosis-in-prostate-amp-IdAOlQe0WM
SP - 37
EP - 37
VL - 24
IS - 2
DP - DeepDyve
ER -