TY - JOUR AU1 - Terada, Mitsuo AB - Breast Cancer Research and Treatment (2018) 172:743–744 https://doi.org/10.1007/s10549-018-4931-7 REBUT TAL LE T TER Challenge for identifying the origin of occult breast cancer for optimizing local therapy Mitsuo Terada Received: 29 July 2018 / Accepted: 17 August 2018 / Published online: 15 October 2018 © Springer Science+Business Media, LLC, part of Springer Nature 2018 Dear Editor, out or replaced by tumor cells arising from the EBT; like the absence of normal ducal basal cells in ductal carcinoma We have read the letter “Theoretical possibility of primary in situ. We will keep on searching for EBT remaining in breast cancer originates from ectopic breast tissue (EBT) OBC samples. in axillary lymph nodes” from Dr. Yang and Dr. Lv. We Our hypothesis is aimed at optimizing local treatment for are grateful for receiving the important and insightful com- OBC patients. Pre-operative intensive check-up for bilateral ments on our review article and hypothesis of occult breast breasts including accessory breast is extremely important cancer (OBC). In our article [1], we hypothesized that OBC as the authors of the letter suggested. In terms of omitting may originate from EBT in axillary lymph nodes (ALNs). mastectomy or whole breast radiotherapy (WBRT) for OBC They have raised three points as follows. First, TI - Challenge for identifying the origin of occult breast cancer for optimizing local therapy JF - Breast Cancer Research and Treatment DO - 10.1007/s10549-018-4931-7 DA - 2018-10-15 UR - https://www.deepdyve.com/lp/springer-journals/challenge-for-identifying-the-origin-of-occult-breast-cancer-for-IXNetu0X0v SP - 743 EP - 744 VL - 172 IS - 3 DP - DeepDyve ER -