TY - JOUR AU - Fakih-Gomez, Nabil AB - IntroductionThe rise in clinical procedures utilizing dermal fillers necessitates preparedness for potential emergencies. Effective management of complications arising from filler use, including vascular occlusions and allergic reactions, hinges on the availability of the appropriate pharmacological supplies.MethodsA two-tiered search in PubMed and Google Scholar was conducted to identify essential drugs for dermal filler emergencies. An initial 10-year review used keywords “Dermal Fillers,” “vascular occlusion,” and “hyaluronidase,” followed by a targeted search on “Resuscitation guidelines,” “anaphylaxis management,” “allergy fillers,” and “lidocaine.” This article outlines the critical drug inventory for emergency kits to manage filler-related complications effectively.ResultsAn ORA classification system (Obligatory, Recommended, Advisable) is introduced to categorize essential drugs according to urgency and clinical necessity. The required drugs are grouped based on their application in cases of vascular occlusion without ocular involvement, vascular occlusion with ocular involvement, anaphylactic reactions, cardiopulmonary resuscitation and hemodynamic disorders, delayed reactions, and aseptic, oxygen, and topical treatments. Additionally, the importance of meticulous drug inventory management—including tracking of stock entry, exit, and expiration dates—is emphasized to reduce the risk of shortages.ConclusionEnsuring that filler emergency kit is well stocked with vital pharmacological supplies is imperative for effective emergency management during filler procedures. Adopting systematic inventory practices and utilizing the ORA classification can enhance preparedness and patient safety.Level of Evidence VThis journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266. TI - Essential Pharmaceutical Drugs in the Filler Emergency Kit JF - Aesthetic Plastic Surgery DO - 10.1007/s00266-025-04808-w DA - 2025-03-31 UR - https://www.deepdyve.com/lp/springer-journals/essential-pharmaceutical-drugs-in-the-filler-emergency-kit-IVWEtZM91f SP - 1 EP - 14 VL - OnlineFirst IS - DP - DeepDyve ER -