TY - JOUR
AU - Fanelli, Roberto
AB - The capability of high performance liquid chromatography/ion spray mass spectrometry (HPLC/ISP‐MS) and HPLC/ISP‐tandem mass spectrometry (HPLC/ISP‐MS/MS) were investigated to achieve mass separation as well as structural characterization of taxol metabolites directly in rat bile, without their previous isolation. HPLC/ISP‐MS yielded information on the molecular weights of several hydroxylated derivatives while HPLC/ISP‐MS/MS allowed the on‐line structural characterization of all metabolites present in different ratios in rat bile.
TI - Structural characterization of mono‐ and dihydroxylated metabolites of paclitaxel in rat bile using liquid chromatography/ion spray tandem mass spectrometry
JF - Rapid Communications in Mass Spectrometry
DO - 10.1002/(SICI)1097-0231(19970615)11:9<1025::AID-RCM956>3.0.CO;2-M
DA - 1997-01-15
UR - https://www.deepdyve.com/lp/wiley/structural-characterization-of-mono-and-dihydroxylated-metabolites-of-IRj2rzCBoq
SP - 1025
EP - 1032
VL - 11
IS - 9
DP - DeepDyve
ER -