TY - JOUR
AU1 - Yılmaz, Hayati
AU2 - Köylü, Mehmet Talay
AU3 - Yılmaz, Alper Can
AU4 - Durukan, Ali Hakan
AU5 - Uysal, Yusuf
AB - Objectives: To investigate the agreement between optical coherence tomography (OCT) and OCT-based angiography (OCT-A) in estimating retinal nerve fiber layer thickness (RNFLT) and evaluate the associations between peripapillary vessel density (VD) and RNFLT measurements obtained with both devices.Materials and Methods:The AngioVue (Optovue Inc., Fremont, CA, USA) and Spectralis (Heidelberg Engineering, Heidelberg, Germany) images of 325 patients were screened retrospectively. RNFLT values were recorded using both devices. The intraclass correlation coefficient (ICC) and Bland-Altman plots were obtained to investigate the agreement between the devices. Age- and intraocular pressure-corrected associations between VD and RNFLT measured by the two devices were analyzed using linear regression models.Results:ICC revealed excellent agreement for global, superior, inferior, and temporal RNFLT and good agreement for the nasal quadrant (ICC=0.895, 0.936, 0.923, 0.887, and 0.614, respectively). The Bland-Altman plots showed poor agreement for all measurements with a large span of limits of agreement and significant proportional bias (p<0.05). VD was found to be strongly associated with the RNFLT measurements of both devices (p<0.001).Conclusion:The disagreement between the devices should be considered in clinical practice, and the data should not be used interchangeably. The association of the peripapillary VD with RNFLT using both devices indicated that RNFLT assessed by the AngioVue could be used in glaucoma management along with VD.
TI - Agreement Between Standard Optical Coherence Tomography and Optical Coherence Tomography-Based Angiography in Estimating Retinal Nerve Fiber Layer Thickness
JF - Turkish Journal of Ophthalmology
DO - 10.4274/tjo.galenos.2020.18488
DA - 2020-10-30
UR - https://www.deepdyve.com/lp/pubmed-central/agreement-between-standard-optical-coherence-tomography-and-optical-IO3FZDEReC
SP - 264
EP - 270
VL - 50
IS - 5
DP - DeepDyve
ER -