TY - JOUR
AU - Nishikii, Hidekazu
AB - International Journal of Hematology (2020) 112:433–434 https://doi.org/10.1007/s12185-020-02976-w IMAGES IN HEMATOLOGY FDG‑PET imaging and histopathology in neuroleukemiosis with acute myeloid leukemia 1 2 3 1 Yusuke Kiyoki  · Ryota Matsuoka  · Tomohiro Kaneta  · Hidekazu Nishikii Received: 27 April 2020 / Revised: 24 July 2020 / Accepted: 20 August 2020 / Published online: 31 August 2020 © Japanese Society of Hematology 2020 A 30-year old man demonstrated myeloblastosis in the the bone marrow. An electrophysiologic test revealed the peripheral blood and massive infiltration of leukemic blasts delayed nerve conduction in the peripheral nerves. There − + in the bone marrow. The myeloblasts showed CD7 CD11b were no significant abnormalities in brain MRI. Notably, − + − + 18 18 CD14 CD33 CD34 CD56 by flow cytometry, and posi- FDG-PET images demonstrated accumulations of FDG tive peroxidase and negative esterase stainings. Cytogenetic in multiple peripheral nerves (Fig. 1a). He eventually died analysis revealed a complex karyotype. He was diagnosed due to disease progression. Autopsy revealed apparent infil- as acute myeloid leukemia, without maturation (FAB clas- tration of leukemic cells into the peripheral nerve roots, in sification: AML-M1). which FDG accumulation was evident (Fig. 1b–d). Neu- Remission induction chemotherapy with idarubicin and roleukemiosis is a rare complication of myeloid malignan- cytarabine resulted 
TI - 18FDG-PET imaging and histopathology in neuroleukemiosis with acute myeloid leukemia
JF - International Journal of Hematology
DO - 10.1007/s12185-020-02976-w
DA - 2020-10-31
UR - https://www.deepdyve.com/lp/springer-journals/18fdg-pet-imaging-and-histopathology-in-neuroleukemiosis-with-acute-ID0sh68gnk
SP - 433
EP - 434
VL - 112
IS - 4
DP - DeepDyve
ER -