TY - JOUR
AU - LORIAUX, D., LYNN
AB - Spontaneous toxemia occurs in approximately 6% of pregnancies in patas monkeys (Erythrocebus patas). To assess further the relevance of this animal as a model system for toxemia of pregnancy in humans, we characterized the endocrine profile of the patas pregnancy by analyzing weekly blood samples for estrone, estradiol, estriol, progesterone, aldosterone, and PRA throughout gestation. The profiles obtained bear striking resemblance to those described for human pregnancy, an unexpected finding since the patas monkey is not a higher hominoid. We conclude that the patas monkey may provide a model of toxemia relevant to study of the human disorder and is superior to other animal models which require surgical manipulation and are characterized by secondary hyperreninemia. (Endocrinology116: 1090–1093,1985) This content is only available as a PDF. Copyright © 1985 by The Endocrine Society
TI - Endocrine Profile of Pregnancy in the Patas Monkey (Erythrocebus patas)
JF - Endocrinology
DO - 10.1210/endo-116-3-1090
DA - 1985-03-01
UR - https://www.deepdyve.com/lp/oxford-university-press/endocrine-profile-of-pregnancy-in-the-patas-monkey-erythrocebus-patas-Hw92KZAQQP
SP - 1090
EP - 1093
VL - 116
IS - 3
DP - DeepDyve
ER -