TY - JOUR AU - Wen, Joanne AB - Background To characterize how prior incisional glaucoma surgery affects the intraocular pressure (IOP) elevation immediately following intravitreal anti-VEGF injections (IVI). Methods Single institution, experimental study. Patients with a history of incisional glaucoma surgery who were receiving anti- VEGF injections were recruited as well as control eyes. Pre- and post-injection IOP measurements were compared as well as time to recovery to within 5 and 10 mmHg of baseline IOP. Results Ten eyes with a history of glaucoma surgery and 29 control eyes receiving anti-VEGF injections were included. The most common indication for intravitreal anti-VEGF injection was proliferative diabetic retinopathy in both surgical and control eyes (50% vs 45%, p = 1.00). Post-injection IOP was significantly decreased compared to baseline IOP after anti-VEGF injection in surgical versus control eyes (26.5 ± 8.9 mmHg vs 44.2 ± 8.5 mmHg, respectively, p <0.001). The mean change in IOP following intravitreal anti-VEGF injection was lower in surgical eyes (10.7 ± 6.6 mmHg vs 28.6 ± 8.3 mmHg, p < 0.001). Themean time fortheIOPtoreturn towithin10mmHgofpre-injectionIOP waslessinsurgical eyes (5.2 ± 4.1 min vs 13.3 ± 7.6 min, p = 0.002). Conclusions Eyes with prior incisional glaucoma surgery demonstrated a significantly lower post-injection IOP elevation and a TI - Effect of prior glaucoma surgery on intraocular pressure immediately after anti-vascular endothelial growth factor injection JF - Graefe's Archive for Clinical and Experimental Ophthalmology DO - 10.1007/s00417-019-04431-x DA - 2019-08-06 UR - https://www.deepdyve.com/lp/springer-journals/effect-of-prior-glaucoma-surgery-on-intraocular-pressure-immediately-HuEe7eHC9C SP - 2489 EP - 2494 VL - 257 IS - 11 DP - DeepDyve ER -