TY - JOUR AU - CHICK, ERNEST W. AB - Abstract The low-pressure mercury vapor lamp has unique and highly desirable features for corneal ultraviolet phototherapy. The emitted rays are highly germicidal,1 virtually monochromatic at 2,537 A.,1 and totally absorbed by the cornea2 with low keratitis effect.3 Previous work in corneal ultraviolet phototherapy utilized nonspecific polychromatic radiation which is less germicidal and more toxic than 2,537 A., but good results were still frequently obtained.4,5 The corneal phototherapeutic use of the low-pressure mercury vapor lamp has not been previously reported in the literature. This paper will present: (1) the theoretical basis of corneal ultraviolet phototherapy and the advantages of using this lamp by comparing its only significant spectral radiation, 2,537 A., with the ideal phototherapeutic wavelength, and (2) a clinical and histological study of eyes irradiated by this lamp. I. Theoretical Basis for Corneal Ultraviolet Phototherapy The theoretically ideal wavelength for corneal ultraviolet phototherapy should have the following References 1. The lamp unit contained the following components; 794H Sterilamp bulb (Westinghouse); standard 4 watt, 794 ballast, 118 volts, 0.35 amps., 60 cycle, U. L. approved transformer (Keystone Transformer Co., Philadelphia 44, Pa.); and intermediate screw-type, keyless, lamp-holder socket No. 1T4613 (Bryant Electric Co., Bridgeport, Conn.). Unit assembled by L. D. Nagy. 2. Ultraviolet (2,537 A.) Electric Meter, 110 volts, 60 a.c.; L. D. Nagy, 25 Mt. Vernon Road, Upper Montclair, N.J. 3. Nagy, R.: Ultraviolet Lamps; Industrial Research Activities and Objectives , J. Invest. Derm. 32:175, 1959.Crossref 4. Kinsey, V. E.: Spectral Transmission of the Eye to Ultraviolet Radiations , Arch. Ophthal. 39: 508, 1948.Crossref 5. Cogan, D. G., and Kinsey, V. E.: Action Spectrum of Keratitis Produced by Ultraviolet Radiation , Arch. Ophthal. 35:670, 1946.Crossref 6. Duke-Elder, W. S.: Ultra-Violet Light in the Treatment of Ophthalmic Diseases; Local Phototherapy , Brit. J. Ophthal. 12:353, 1928.Crossref 7. Birch-Hirschfeld, A., and Hoffman, W.: Die Lichtbehandlung in der Augenheilkunde , Abstract, Brit. J. Ophthal. 12:665, 1928. 8. Duke-Elder, W. S.: Textbook of Ophthalmology , Vol. 6, St. Louis, The C. V. Mosby Company, 1954, p. 6450. 9. Sharp, D. G.: Lethal Action of Short Ultraviolet Rays on Several Common Pathogenic Bacteria , J. Bact. 37:447, 1939. 10. Phillips, G. B., and Hanel, E.: Microbiological Applications of Ultraviolet Radiations, Special Report 211, Camp Detrick, Md., January, 1956. 11. Lamp Division, Westinghouse Electric Corp. 10. Sharp, D. G.: Personal communication to the author. 12. Kaufman, H. E.; Nesburn, A. B., and Maloney, E.: Unpublished data. 13. Duke-Elder, W. S.: Histological Study on the Action of Short-Waved Light Upon the Eye, with a Note on "Inclusion Bodies," Brit. J. Ophthal. 13:1, 1929.Crossref 14. Busche, W.; Friedenwald, J. S., and Moses. S. G.: Effects of Ultraviolet Irradiation on Corneal Epithelium: Mitosis, Nuclear Fragmentation, Post-Traumatic Cell Movements, Loss of Tissue Cohesion , J. Cell. Comp. Physiol. 26:147, 1945.Crossref 15. Hart, D.: Bactericidal Ultraviolet Radiation in the Operating Room: Twenty-Nine Year Study for Control of Infections , J.A.M.A. 172:1019, 1960Crossref 16. Hart, D., and Nicks, J.: Ultraviolet Radiation in the Operating Room: Intensities Used and Bactericidal Effects , Arch. Surg. 82:449, 1961.Crossref 17. Hudnell, A. B., Jr.: Unpublished data. 18. Anderson, W. B., Jr., and Chick, E. W: Myco-Keratitis: Treatment of Fungal Corneal Ulcers with Amphotericin B and Mechanical Debridement, South. Med. J., to be published. TI - Corneal Ultraviolet Phototherapy JF - Archives of Ophthalmology DO - 10.1001/archopht.1962.00960030308003 DA - 1962-09-01 UR - https://www.deepdyve.com/lp/american-medical-association/corneal-ultraviolet-phototherapy-HNCnLSL3vE SP - 304 EP - 312 VL - 68 IS - 3 DP - DeepDyve ER -