TY - JOUR AU1 - Lewis, S. M. AB - ICSH acquired types. It must, however, be emphasized that the decision whether splenectomy would be of value must take account of tlic clinical features, haematological and other laboratory data. Because evcn small technical variations msy result in large discrepancies in surface counting data, it is of particular importance that a standardized method of '' Cr surface counting should be adopted. The purpose of this documcnt is to describe rccommended mcthods which take account of a number of factors which have been found to bc causes of error. As the data obtained by surface counting studies depend on the detector system uscd and the anatomical positions selected for counting, it will be necessary to define the sigiiificaiice of the data obtained by the recommeiided methods, before definite criteria for deciding on splenectomy can be established. 2. METHODOLOGY Localization o Spleen f Since the position of the spleen may vary widely from patient to patient, the procedure requires the localization of the organ in each individual patient. A widely used method is to determine the point in the left hypochondrium at which the highest counting rate is observed 30-60 min after injection of the 51Cr-labelled cells (see 2.5 below). Subsequent TI - Recommended Methods for Surface Counting to Determine Sites of Red‐Cell Destruction JF - British Journal of Haematology DO - 10.1111/j.1365-2141.1975.tb00538.x DA - 1975-06-01 UR - https://www.deepdyve.com/lp/wiley/recommended-methods-for-surface-counting-to-determine-sites-of-red-H4DuRHM0VC SP - 249 VL - 30 IS - 2 DP - DeepDyve ER -