TY - JOUR
AU - Chong, Charing C. N.
AB - PurposeTo compare the peri-operative and long-term survival outcomes of minimally invasive liver resection (MILR) (robotic or laparoscopic) with open liver resection (OLR) in patients with hepatocellular carcinoma (HCC).MethodsData of patients who underwent liver resection for HCC were reviewed from a prospectively collected database. Outcomes of MILR were compared with those of OLR. A propensity score matching analysis with a ratio of 1:1 was performed to minimise the potential bias in clinical pathological factors.ResultsFrom January 2003 to December 2017, a total of 705 patients underwent liver resection for HCC. Amongst them, 112 patients received MILR and 593 patients received OLR. After propensity score matching, there were 112 patients in each of the MILR and OLR groups. Patients were matched by age, sex, hepatitis status, presence of cirrhosis, platelet count, albumin level, bilirubin level, alkaline phosphatase (ALP) level, alanine transferase (ALT) level, creatinine level, tumour differentiation, tumour size, tumour number, presence of tumour rupture, presence of vascular invasion, extent of liver resection (minor/major) and difficulty score. The 1-, 3- and 5-year overall survival rates were 94.4%, 90.4% and 82.3% in the MILR group vs 95.4%, 80.5% and 71.8% in the open group (p = 0.240). The 1-, 3- and 5-year disease-free survival rates were 81.0%, 63.1% and 55.8% in the MILR group vs 79.1%, 58.1% and 45.7 in the open group (p = 0.449). The MILR group demonstrated significantly less blood loss (p < 0.001), less blood transfusion (p = 0.004), lower post-operative complications (p < 0.001) and shorter hospital stay (p < 0.001) when compared with the OLR group.ConclusionsOur data shows MILR yielded superior post-operative outcomes to OLR, with comparable survival outcomes.
TI - Minimally invasive versus open liver resection for hepatocellular carcinoma: a propensity score matching analysis of 224 patients
JF - Langenbeck s Archives of Surgery
DO - 10.1007/s00423-023-02857-w
DA - 2023-03-14
UR - https://www.deepdyve.com/lp/springer-journals/minimally-invasive-versus-open-liver-resection-for-hepatocellular-H09iA0KDCk
VL - 408
IS - 1
DP - DeepDyve
ER -