TY - JOUR
AU - Tsantili-Kakoulidou, Anna
AB - The interaction of some substituted coumarin derivatives with the stable 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical was analysed by means of multivariate statistics using a variety of molecular descriptors. The compounds contain a conjugated double bond system, which was considered to be an essential structural characteristic for the free-radical scavenging activity. Partial least-square analysis led to an adequate two-component model based on bulk descriptors and the electronic properties concerning atoms involved or next to the double-bond system.
TI - Analysis of the interaction of substituted coumarins with the DPPH free radical by means of multivariate statistics
JF - Journal of Pharmacy and Pharmacology
DO - 10.1211/0022357044157
DA - 2004-09-01
UR - https://www.deepdyve.com/lp/oxford-university-press/analysis-of-the-interaction-of-substituted-coumarins-with-the-dpph-GlISCiidA0
SP - 1191
EP - 1194
VL - 56
IS - 9
DP - DeepDyve
ER -