TY - JOUR AU - Sehgal, P.B. AB - S172 SPO Abstracts NITRIC OXIDE DONORS INDUCE CERVICAL RIPENING IN FIRST TRIMESTER HUMAN PREGNANCY. A.~ Thomson, ~ CB. Lunmz, x A.D. Cameron, L T. Cameron,~ LA. Oreer,~ .~E. Norman3 Dept Ob/Gyn, Univ. of Glasgow, Glasgow, Scotland. OBJECTIVE: To deterntine the effects of the nitric oxide (NO) donors isosorbide mononitrate (IMN), and glyceryl trinitrate (GTN) on the force required to dilate the human cervix during surgical termination in the first trimester. STUDY DESIGN: A prospective, double-blind trial was performed involving 41 primigravid women referred for surgical terntination by vacuum aspiration in the first trimester. The patients were randomized to receive per vaginam, 3 hours prior to surgery, either the N O donor, IMN 40 rag, the N O donor, GTN 500 b~g, the prostaglandin analogue, gemeprost h n g or no treammnt (vaginal examination only). The force in Newtons, (N) required to dilate the cervix to 8 turn was measured with a force sensing apparatus coupled to the cervical dilators. Statistical analysis was performed using Mann-Whimey tests. RESULTS: Ten women received IMN, 9 received GTN, 11 had gemeprost and 11 received no treatment. There was no significant diifi~rence in age, race or gestational age between the groups. A significantly TI - Biochemical characterization of human interleukin-6 in amniotic fluid JF - American Journal of Obstetrics and Gynecology DO - 10.1016/S0002-9378(97)80669-2 DA - 1997-01-01 UR - https://www.deepdyve.com/lp/wolters-kluwer-health/biochemical-characterization-of-human-interleukin-6-in-amniotic-fluid-GaMmDoTcZ0 SP - S172 VL - 176 IS - 1 DP - DeepDyve ER -