TY - JOUR
AU - Fasciolo, Juan Carlos
AB - The biological effects of Rauwolfia schueli are essentially the same as those of the pure alkaloid reserpine and the crude compound R. serpentina in the rat. No difference in relative potency between the small and large roots of large trees of the R. schueli species was apparent when either reserpine or R. serpentina was employed as the standard. R. schueli was estimated to be about 1/630 as active as reserpine. In terms of reserpine-like activity, this species appeared to be more potent than R. serpentina and by comparison with the results of others about as potent as R. canescens but more potent than R. heterophylla. Within the range of doses selected, blood pressure did not appear to be an adequate index for measuring reserpine-like activity in the rat.
TI - The Biological Assay of Rauwolfia Schueli
JO - Journal of Pharmacy and Pharmacology: An International Journal of Pharmaceutical Science
DO - 10.1111/j.2042-7158.1960.tb12709.x
DA - 1960-09-01
UR - https://www.deepdyve.com/lp/oxford-university-press/the-biological-assay-of-rauwolfia-schueli-G2XK5jBwG9
SP - 557
EP - 561
VL - 12
IS - 1
DP - DeepDyve
ER -