TY - JOUR AU - WARIN, ROBERT P. AB - Br. J. Derm. (1971) 84, 227. Department of Dermatology, Bristol General Hospital AN ASSESSMENT OF THE EOLE OF CANDIDA ALBICANS AND FOOD YEASTS IN CHRONIC URTICARIA JEAN JAMES AND ROBERT P. WARIN SUMMARY.—In 100 patients with chronic urticaria seen consecutively in the Outpatient Department of the Bristol General Hospital, prick tests to Candida albicans gave either a Type I and/or a Type III (Gell and Coombs) reaction in 36. Challenge tests to C. albicans extract and food yeasts {Saccharomyces cerevisiae), administered in a double blind manner, caused an exacerbation of the urticaria in a significantly greater proportion of the patients vv'ho had given a positive prick test than of those who had given a negative prick tes t to C. albicans. Anti- candida therapy and a low yeast diet gave significant clinical improvement in the patients with positive prick tests. In 10 patients with a positive C. albicans prick test serum antibodies and the IgE level were estimated; the results did not differ from those in norma l controls. It would appear that in about 26% of patients with chronic urticaria C. albicans sensitivity is an important factor, tiiat there may be cross reactions between this organism and food TI - AN ASSESSMENT OF THE ROLE OF CANDIDA ALBICANS AND FOOD YEASTS IN CHRONIC URTICARIA JF - British Journal of Dermatology DO - 10.1111/j.1365-2133.1971.tb14212.x DA - 1971-03-01 UR - https://www.deepdyve.com/lp/oxford-university-press/an-assessment-of-the-role-of-candida-albicans-and-food-yeasts-in-Fj3oOKLcYC SP - 227 EP - 237 VL - 84 IS - 3 DP - DeepDyve ER -