TY - JOUR
AU1 - Rosato, Edoardo
AU2 - Cianci, Rosario
AU3 - Barbano, Biagio
AU4 - Menghi, Ginevra
AU5 - Gigante, Antonietta
AU6 - Rossi, Carmelina
AU7 - Zardi, Enrico M
AU8 - Amoroso, Antonio
AU9 - Pisarri, Simonetta
AU1 - Salsano, Felice
AB - Acta Pharmacologica Sinica (2009) 30: 1283–1288 npg © 2009 CPS and SIMM All rights reserved 1671-4083/09 $32.00 www.nature.com/aps Original Article N-acetylcysteine infusion reduces the resistance index of renal artery in the early stage of systemic sclerosis 1 2 2 1 2 1 Edoardo ROSATO , Rosario CIANCI , Biagio BARBANO , Ginevra MENGHI , Antonietta GIGANTE , Carmelina ROSSI , Enrico 3 4 1 1, M ZARDI , Antonio AMOROSO , Simonetta PISARRI , Felice SALSANO 1 2 Sapienza University of Rome Department of Clinical Medicine, Clinical Immunology Unit-Scleroderma Center, Italy; Sapienza Univer- sity of Rome Department of Clinical Medicine, Nefrology Unit, Italy; Department of Clinical Medicine, “Campus Bio-Medico” University, Rome, Italy; Sapienza University of Rome Department of Clinical Medicine, Italy Aim: To evaluate resistance index (RI) changes in renal artery after N-acetylcysteine infusion in patients with systemic sclerosis. Methods: In an open-label study 40 patients with systemic sclerosis (SSc) were treated with N-acetylcysteine (NAC) iv infusion over 5 -1 -1 consecutive hours, at a dose of 0.015 g·kg ·h . Renal haemodynamic effects were evaluated by color Doppler examination before and after NAC infusion. Results: NAC infusion significantly reduced RI in a group of sclerodermic patients with early/active 
TI - N-acetylcysteine infusion reduces the resistance index of renal artery in the early stage of systemic sclerosis
JF - Acta Pharmacologica Sinica
DO - 10.1038/aps.2009.128
DA - 2009-09-04
UR - https://www.deepdyve.com/lp/springer-journals/n-acetylcysteine-infusion-reduces-the-resistance-index-of-renal-artery-Ey7vTsPb8h
SP - 1283
EP - 1288
VL - 30
IS - 9
DP - DeepDyve
ER -