TY - JOUR
AU1 - Wang, Hsin-Yao
AU2 - Lin, Ting-Wei
AU3 - Chiu, Sherry Yueh-Hsia
AU4 - Lin, Wan-Ying
AU5 - Huang, Song-Bin
AU6 - Hsieh, Jason Chia-Hsun
AU7 - Chen, Hsieh Cheng
AU8 - Lu, Jang-Jih
AU9 - Wu, Min-Hsien
AU1 - 
AB - Background: Colorectal cancer screening by fecal occult blood testing has been an important public health test and shown to reduce colorectal cancer–related mortality. However, the low participation rate in colorectal cancer screening by the general public remains a problematic public health issue. This fact could be attributed to the complex and unpleasant operation of the screening tool. Objective: This study aimed to validate a novel toilet paper–based point-of-care test (ie, JustWipe) as a public health instrument to detect fecal occult blood and provide detailed results from the evaluation of the analytic characteristics in the clinical validation. Methods: The mechanism of fecal specimen collection by the toilet-paper device was verified with repeatability and reproducibility tests. We also evaluated the analytical characteristics of the test reagents. For clinical validation, we conducted comparisons between JustWipe and other fecal occult blood tests. The first comparison was between JustWipe and typical fecal occult blood testing in a central laboratory setting with 70 fecal specimens from the hospital. For the second comparison, a total of 58 volunteers were recruited, and JustWipe was compared with the commercially available Hemoccult SENSA in a point-of-care setting. Results: Adequate amounts of fecal specimens were collected using the toilet-paper device 
TI - Novel Toilet Paper–Based Point-Of-Care Test for the Rapid Detection of Fecal Occult Blood: Instrument Validation Study (Preprint)
DO - 10.2196/preprints.20261
DA - 2020-05-19
UR - https://www.deepdyve.com/lp/unpaywall/novel-toilet-paper-based-point-of-care-test-for-the-rapid-detection-of-ELudXSKB2a
DP - DeepDyve
ER -