TY - JOUR
AU - Fujimoto, Yukari
AB - Newly developed synthetic methods for monoglycosylceramides enabled representative brain glycolipid synthesis. Immunomodulatory activities of the glycolipids were examined via CD1d and Mincle. CD1d strongly bound endogenous GlcCer with longer unsaturated fatty acids (e.g., C24:1), partly inhibiting other antigens and stabilizing CD1d's immunological role in presenting lipid antigens to NKT cells.
TI - Lipid structure-dependent CD1d functional stabilization and immunomodulation of endogenous glucosylceramides
JF - Chemical Communications
DO - 10.1039/d5cc00003c
DA - 2025-03-09
UR - https://www.deepdyve.com/lp/royal-society-of-chemistry/lipid-structure-dependent-cd1d-functional-stabilization-and-Dv6tq9YEtP
SP - 5154
EP - 5157
VL - 61
IS - 27
DP - DeepDyve
ER -