TY - JOUR
AU - Smith, A. D.
AB - Somatostain‐immunoreactive neurons in the rat neostriatum were studied by correlated light and electron microscopy using the peroxidase‐antipe‐roxidase immunocytochemical technique. Immunoreactivity was localized in neuronal perikarya and processes. The perikarya were of spindle or fu‐siform shape (average length 16.9 μm) and were found in all parts of the neostriatum. From each neuron there arose two to four straight immuno‐reactive dendritelike processes, which could frequently be traced as far as about 130 μm from their perikaryon. Immunoreactive varicose axonlike processes were occasionally found, some of which were proximal axons of identified immunoreactive cells. Nine of the light microscopically identified neurons showing somatostatin‐immunoreactivity were studied in the elec‐tron microscope; two of them had proximal axons with varicosities. Each neuron had an oval or elongated nucleus, which was always indented. These morphological features correspond well to those of certain “medium‐size aspiny” neurons classified by Golgi studies. Although the immunoreactive endproduct was diffusely located throughout the neuron, it was character‐istically located in the saccules and large granules (diameter 133 nm) of the Golgi apparatus, and large immunoreactive vesicles of similar size to those in the Golgi apparatus frequently occurred in all parts of axon. Very little synaptic input was found on the perikarya and dendrites of somato‐statin‐immunoreactive neurons. The perikarya and proximal dendrites re‐ceived both symmetrical and asymmetrical synaptic input, while the distal dendrites usually received boutons that formed asymmetrical contacts.
TI - Fine structural studies on a type of somatostatin‐immurioreactive neuron and its synaptic connections in the rat neostriatum: A correlated light and electron microscopic study
JF - The Journal of Comparative Neurology
DO - 10.1002/cne.902140102
DA - 1983-10-10
UR - https://www.deepdyve.com/lp/wiley/fine-structural-studies-on-a-type-of-somatostatin-immurioreactive-DJvfl4MGyS
SP - 1
EP - 16
VL - 214
IS - 1
DP - DeepDyve
ER -