TY - JOUR AU - McEwan, G.C. AB - British Journal of Dermatology (1981) 105, 113. Correspondence SIR, There is some evidence that patients with defective tear secretion associated with Sjogren's syn- drome or the sicca syndrome may respond to treatment with fatty acids, pyridoxine and ascorbic acid (Horrobin & Campbell, 1980). While evaluating this treatment we have found four patients who had brittle nails whose nail and eye conditions improved simultaneously. The patients were treated with the following regime: evening primrose oil (Efamol G), a rich source of essential fatty acids containing both linoleic and gammalinolenic acids, two capsules three times per day; pyridoxine, a vitamin which is required for essential fatty acid metabolism, 25-50 mg per day; ascorbic acid, which etihances conver- sion of essential fatty acids to prostaglandin E, , 2-3 g per day (Horrobin & Campbell, 1980). Patient I A 55-year-old woman gave a 6-month history of dry gritty eyes and brittle nails which were prone to split when manicured. On the above regime her eye condition gradually improved and after i month she spontaneously reported that her nails had become fully normal. Patient 2 A 72-year-old woman had an 8-month history of dry, gritty eyes and a 6-month history of her nails splitting TI - Treatment of brittle nails and dry eyes JO - British Journal of Dermatology DO - 10.1111/j.1365-2133.1981.tb00893.x DA - 1981-07-01 UR - https://www.deepdyve.com/lp/oxford-university-press/treatment-of-brittle-nails-and-dry-eyes-D00e11cFDY SP - 113 EP - 113 VL - 105 IS - 1 DP - DeepDyve ER -