TY - JOUR
AU - Huch, R.
AB - Gynecol, obstet. Invest. 15: 365-371 (1983) The Predictive Value of the DHAS Loading Test in Pregnancies for Intrauterine Fetal Growth Retardation P.J. Keller, A. Lysikiewicz, R. Much Department of Obstetrics and Gynecology, University of Zurich, Switzerland Evaluation of placental function in risk pregnancies is a still conflicting problem despite a great number of studies on the predictive value of bio­ chemical and biophysical parameters. Since 1969 various modifications of placental loading tests with estrogen precursors such as déhydroépiandros­ térone sulfate (DHAS) have been proposed. This diagnostic procedure is based on the assumption that an impaired trophoblast function is reflected by delayed conversion of exogenously administered steroids. While the the­ oretical interest of such methods is undisputed, the practicability and diag­ nostic accuracy remain a matter of controversy. It seemed to be worthwhile to reevaluate the problem in carefully selected groups of women with normal pregnancies and with proven intra­ uterine fetal growth retardation. For comparison, the presently available modifications of the loading test, i.e. the rate of disappearance of DHAS as well as the aromatization and conversion into estrone, estradiol-17ß and estriol were studied. Patients and Methods A total o f 40 DHAS loading tests were performed in primi- 
TI - The Predictive Value of the DHAS Loading Test in Pregnancies for Intrauterine Fetal Growth Retardation
JF - Gynecologic and Obstetric Investigation
DO - 10.1159/000299433
DA - 2010-01-01
UR - https://www.deepdyve.com/lp/karger/the-predictive-value-of-the-dhas-loading-test-in-pregnancies-for-C2yeOs53zc
SP - 365
EP - 371
VL - 15
IS - 6
DP - DeepDyve
ER -