TY - JOUR
AU - A, Bonner-Jackson,
AB - Objective: To determine the rate of change in Montreal Cognitive Assessment (MoCA) scores over time among patients evaluated in a memory disorders clinic. Method: At each visit, a physician assigned the following diagnoses based on clinical evaluation; cognitively intact (CI); cognitive dysfunction- not neurodegenerative (CD); Mild cognitive impairment (MCI), Alzheimer’s disease (AD), and other dementia (FTD, DLB, PPA). Of 1632 patients included in this study, 470 patients completed 2 or more MoCA’s with same diagnosis over a 6-year period. Results: Of the 339 patients with 823 visits, 13 remained classified as cognitively intact, 41 as cognitive dysfunction (did not meet criteria for MCI), 180 MCI, 45 AD, and 60 classified as other dementia. Average age 68.0 (SD = 8.5) and 69% had more than 12 years of education. There were significant group differences in age and baseline MoCA score. The average time between MoCA completions was 390.6 days (SD = 273.7). Results of the mixed-effects linear regression model showed about 1 point/year change in patients with MCI (estimate = −0.95, P = 0.04) as well as patients in “other dementia” category (estimate = −1.08, P = 0.039) compared to those cognitively intact. Patients with AD declined 2.19 points/year compared to the cognitively intact (P < 0.001). Age and education were not significantly related to MoCA score. Conclusions: MoCA Total scores showed significant decline in older adults with cognitive impairment over a period of 1–4 years but not in the cognitively intact. Results provide clinically relevant information regarding expected change in MoCA scores over time. © The Author(s) 2018. Published by Oxford University Press. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com. This article is published and distributed under the terms of the Oxford University Press, Standard Journals Publication Model (https://academic.oup.com/journals/pages/open_access/funder_policies/chorus/standard_publication_model)
TI - A - 18Stability of MoCA Scores for Patients Seen in a Memory Disorders Clinic
JO - Archives of Clinical Neuropsychology
DO - 10.1093/arclin/acy061.18
DA - 2018-09-01
UR - https://www.deepdyve.com/lp/oxford-university-press/a-18stability-of-moca-scores-for-patients-seen-in-a-memory-disorders-C0BBaMNuWg
SP - 703
VL - 33
IS - 6
DP - DeepDyve
ER -