TY - JOUR AU - Parisi,, Giovanni AB - Abstract A sensitive and rapid method for the analysis of trazodone (TZD) and its metabolite, 1-(m-chlorophenyl)piperazine (m-CPP), in the serum and urine of rabbits treated with the drug was developed. The assay requires extraction from the biological fluids with adequately buffered organic solvents followed by HPLC. The assay allows good reproducibility, fair recovery, and excellent linearity in the range of 0.6 to 10 µg/mL for TZD and 1.2 to 20 µg/mL for m-CPP. This content is only available as a PDF. TI - Determination of Trazodone® and Its Metabolite, m-CPP, in Serum and Urine by HPLC JF - Journal of Analytical Toxicology DO - 10.1093/jat/10.6.233 DA - 1986-11-01 UR - https://www.deepdyve.com/lp/oxford-university-press/determination-of-trazodone-and-its-metabolite-m-cpp-in-serum-and-urine-BlccCFs1HW SP - 233 EP - 235 VL - 10 IS - 6 DP - DeepDyve ER -