TY - JOUR
AU - Sanford, Jay, P.
AB - Abstract Candiduria has emerged as a common, vexing diagnostic and therapeutic problem over the past 40 years. Treatment by means of bladder irrigation with a solution of amphotericin B has become widely used in clinical practice. However, the specifics of the procedure—concentration of amphotericin B, use of continuous washing vs. instillation with cross-clamping to allow “dwell-times,” and duration of treatment—are based entirely on anecdotal experiences. The published reports and evolution of recommendations are reviewed. A prospective randomized double-blind study is needed to provide answers. In the meantime, administration of 200–300 mL of amphotericin B solution by triple-lumen urethral catheter with cross-clamping for 60–90 minutes seems most appropriate. Irrigation for no longer than 2 days should sufficeif the procedure is to be effective. The optimal concentration of amphotericin B has not been defined; however, 5–10 mg/L appears adequate. This content is only available as a PDF. © 1993 by The University of Chicago
TI - The Enigma of Candiduria: Evolution of Bladder Irrigation with Amphotericin B for Management—From Anecdote to Dogma and a Lesson from Machiavelli
JO - Clinical Infectious Diseases
DO - 10.1093/clinids/16.1.145
DA - 1993-01-01
UR - https://www.deepdyve.com/lp/oxford-university-press/the-enigma-of-candiduria-evolution-of-bladder-irrigation-with-BPxdJruK0y
SP - 145
EP - 147
VL - 16
IS - 1
DP - DeepDyve
ER -