TY - JOUR AU - Molina, J.-M. AB - Infection (2013) 41:663–668 DOI 10.1007/s15010-013-0419-x CLIN ICAL AN D E PID E MIO L OG ICAL STUD Y Invasive pneumococcal disease in HIV-infected adults in France from 2000 to 2011: antimicrobial susceptibility and implication of serotypes for vaccination • • • A.-L. Munier V. de Lastours E. Varon • • J.-L. Donay R. Porcher J.-M. Molina Received: 31 October 2012 / Accepted: 31 January 2013 / Published online: 13 February 2013 Springer-Verlag Berlin Heidelberg 2013 Abstract serotyping was performed by the antiserum agglutination Purpose Invasive pneumococcal diseases (IPD) remain method. frequent and severe events in human immunodeficiency Results Among our study group, 41 HIV-infected adults virus (HIV)-infected subjects despite the use of antiretro- presented 43 IPD during the study period. Of these 41 viral therapy and the availability of vaccines. Our aim was patients, 78 % were men, and the median age was 43 (range to assess the antibiotic susceptibilities and serotypes of 23–62) years. the median CD4 cell count was 184/mm strains responsible for IPD in HIV-infected patients. (6–1,090/mm ), 51 % were receiving antiretroviral therapy, Methods We retrospectively analyzed all Streptococcus and 24 % had plasma HIV-RNA levels of\400 copies/mL. pneumoniae strains isolated from normally sterile sites TI - Invasive pneumococcal disease in HIV-infected adults in France from 2000 to 2011: antimicrobial susceptibility and implication of serotypes for vaccination JF - Infection DO - 10.1007/s15010-013-0419-x DA - 2013-02-13 UR - https://www.deepdyve.com/lp/springer-journals/invasive-pneumococcal-disease-in-hiv-infected-adults-in-france-from-AJR55PHpCv SP - 663 EP - 668 VL - 41 IS - 3 DP - DeepDyve ER -