TY - JOUR
AU1 - Panlilio, Adelisa, L.
AU2 - Beck-Sague, Consuelo, M.
AU3 - Siegel, Jane, D.
AU4 - Anderson, Roger, L.
AU5 - Yetts, Sylvia, Y.
AU6 - Clark, Nancye, C.
AU7 - Duer, Patricia, N.
AU8 - Thomassen, Kathryn, A.
AU9 - Vess, Robert, W.
AU1 - Hill, Bertha, C.
AU1 - Tablan, Ofelia, C.
AU1 - Jarvis, William, R.
AB - Abstract In 1989 we investigated the first instance of Pseudomonas cepacia infections due to intrinsic contamination of a povidone-iodine product. Six patients in a Texas pediatric facility had P. cepacia infection or pseudoinfection (three, peritonitis; one, pseudoperitonitis; and two, pseudobacteremia). Epidemiological studies showed one risk factor for infection of peritoneal fluid with P. cepacia: performance of peritoneal dialysis in the dialysis unit with use of one lot of povidone-iodine later found to be intrinsically contaminated (4/5 vs. 0/16, P = .001). Blood cultures yielded P. cepacia after nurses wiped the tops of blood culture bottles with the povidone-iodine solution before inoculation. P. cepacia was cultured from three povidone-iodine containers used at the hospital and from four containers of the same lot obtained from other health-care facilities in Texas and California. Isolates from patients and the povidone-iodine had similar antibiograms, identical plasmid profiles, and identical DNA banding patterns on the basis of results of ribonucleotide typing. This investigation demonstrates that intrinsic contamination of povidone-iodine solution with P. cepacia can result in infections in addition to colonization and/or pseudoinfection. This content is only available as a PDF. © 1992 by The University of Chicago
TI - Infections and Pseudoinfections Due to Povidone-Iodine Solution Contaminated with Pseudomonas cepacia
JF - Clinical Infectious Diseases
DO - 10.1093/clinids/14.5.1078
DA - 1992-05-01
UR - https://www.deepdyve.com/lp/oxford-university-press/infections-and-pseudoinfections-due-to-povidone-iodine-solution-A00dJnPTrb
SP - 1078
EP - 1083
VL - 14
IS - 5
DP - DeepDyve
ER -