TY - JOUR
AU1 - Tosserams, Anouk
AU2 - Bloem, Bastiaan R.
AU3 - Nonnekes, Jorik
AB - IntroductionGait impairments are among the most disabling motor symptoms of Parkinson's disease (PD). These disturbances can be divided into two major groups, namely: continuously present gait disturbances; and episodically present gait disturbances. Continuous gait disturbances include a reduced step length and height, reduced gait speed, increased gait variability, stooped posture and asymmetrically reduced arm swing.1 Episodic gait disturbances include festination,2 and freezing of gait, the latter being operationally defined as a brief, episodic absence or marked reduction of forward progression of the feet despite the intention to walk.3 As the disease progresses, gait impairment generally becomes increasingly more severe, markedly affecting a person's mobility, independence and quality of life, and causing falls and related injuries.4–6While dopaminergic therapy may have some beneficial effects on gait speed and step length, pharmacological treatment alone rarely suffices to adequately ameliorate gait quality—a problem that worsens further with disease progression, presumably because non‐dopaminergic lesions start to increasingly dominate the underlying pathophysiology.7,8 Therefore, complementary non‐pharmacological interventions form an essential part of the management of gait impairment in PD. The contents of these non‐pharmacological interventions should be tailored to the individual patient, including the person's disease severity and ‐duration, and the specific type of gait disturbance(s).9,10In 
TI - Compensation Strategies for Gait Impairments in Parkinson's Disease: From Underlying Mechanisms to Daily Clinical Practice
JF - Movement Disorders Clinical Practice
DO - 10.1002/mdc3.13616
DA - 2023-08-01
UR - https://www.deepdyve.com/lp/wiley/compensation-strategies-for-gait-impairments-in-parkinson-s-disease-9x9vIifbQ0
SP - S56
EP - S62
VL - 10
IS - S2
DP - DeepDyve
ER -