TY - JOUR AU - OTANI,, TORU AB - The incidence of ovulation after mating was studied in rabbits over approximately a 2-yr period. The results indicate a seasonal variation in this phenomenon, with virtually complete failure of ovulation to occur in the fall of the year. It is postulated that the ovulation reflex is inhibited by a neuroendocrine mechanism. The effects of melatonin and methoxy-tryptophol were studied during periodsof high ovulation rate. A modest inhibitory effect was observed, but complete inhibition was not achieved, nor was the effect increased by prolonged injection. The authors speculate that neither melatonin nor methoxy-tryptophol is solely responsible for the phenomenon of seasonal variation in the ovulation rate. (Endocrinology83: 599, 1968) This content is only available as a PDF. Author notes 1 This research was aided by Grant T-399 from the American Cancer Society. 2 Postdoctoral fellow of the Population Council. Copyright © 1968 by The Endocrine Society TI - Inhibition of Oviolation in the Rabbit: Seasonal Variation and the Effects of Indoles JF - Endocrinology DO - 10.1210/endo-83-3-599 DA - 1968-09-01 UR - https://www.deepdyve.com/lp/oxford-university-press/inhibition-of-oviolation-in-the-rabbit-seasonal-variation-and-the-9UWGyG62l0 SP - 599 EP - 603 VL - 83 IS - 3 DP - DeepDyve ER -