TY - JOUR
AU1 - Cai, Baohua
AU2 - Cui, Yuan
AU3 - Zhou, Jian
AU4 - Wang, Yong‐Bin
AU5 - Yang, Limin
AU6 - Tan, Bin
AU7 - Wang, Jun (Joelle)
AB - A Cu/CPA co‐catalytic system has been developed for achieving the direct hydrophosphinylation of alkynes with phosphine oxides in delivering novel axially chiral phosphorus‐containing alkenes in high yields and excellent enantioselectivities (up to 99 % yield and 99 % ee). DFT calculations were performed to elucidate the reaction pathway and the origin of enantiocontrol. This streamlined and modular methodology establishes a new platform for the design and application of new axially chiral styrene‐phosphine ligands.
TI - Asymmetric Hydrophosphinylation of Alkynes: Facile Access to Axially Chiral Styrene‐Phosphines
JF - Angewandte Chemie
DO - 10.1002/ange.202215820
DA - 2023-01-16
UR - https://www.deepdyve.com/lp/wiley/asymmetric-hydrophosphinylation-of-alkynes-facile-access-to-axially-9BR9k4y7iw
VL - 135
IS - 3
DP - DeepDyve
ER -