TY - JOUR
AU - THOMAS, HENRY M.
AB - Abstract Thyrotoxicosis is conspicuous because of its influence on the rate of the heart, and many of its most interesting symptoms originate in that organ. As early as 1786 Parry realized the connection between cardiac symptomatology and goiter, but to his mind the heart disease was the primary condition. He thought also that exophthalmos, which was present in his eight patients, was secondary to the heart disease. Even Graves, Stokes, and others in the mid 19th century were of the same opinion, and it was not until 1883 and 1885 that Kocher, and, independently, Horsley, recognized the part played in this syndrome by the thyroid hormone. In 1899 Kraus published in Wiener klinische Wochenschrift his concept of the so-called neurotic or thyrotoxic heart from which the current ideas have been developed. At first, interest was centered entirely on the heart in hyperthyroidism. Did toxic diffuse (exophthalmic) goiter produce hypertrophy of the References 1. Thomas, H. M., Jr.: The Heart in Hyperthyroidism , in Diagnosis and Treatment of Cardiovascular Disease , edited by W. D. Stroud, Ed. 4, Philadelphia, F. A. Davis Company, 1950, Vol. 1, p. 364. 2. Smith, F. J.: Clinical Cardiovascular Features of Hyperthyroidism , Heart Bull. 4:102-105 ( (Nov.-Dec.) ) 1955. 3. Surtshin, A., and Rucknagel, D. L.: Vagal Sensitivity and Production of Auricular Fibrillation in Experimentally Hyperthyroid Dogs , Am. Heart J. 45:781-789 ( (May) ) 1953.Crossref 4. Somerville, W., and Levine, S. A.: Angina Pectoris and Thyrotoxicosis , Brit. Heart J. 12: 245-257 ( (July) ) 1950.Crossref 5. Robinson, G. C.: Measurement of Cardiac Output in Man and Its Variations , J. A. M. A. 87:314-317 ( (July 31) ) 1926.Crossref 6. Burwell, C. S.; Smith, W. C., and Neighbors, De W.: Output of Heart in Thyrotoxicosis, with Report of Case of Thyrotoxicosis Combined with Primary Pernicious Anemia , Am. J. M. Sc. 178:157-168 ( (Aug.) ) 1929.Crossref 7. Harrison, T. R., and Blalock, A.: Cardiac Output in Pneumonia in Dog , J. Clin. Invest. 2: 435-455 ( (June) ) 1926.Crossref 8. Rohrer, A.: Vergleich des Sauerstoffverbrauchs überlebender Säugetierorgane im normalen Zustande und nach Fütterung mit Schilddrüsenhormon , Biochem. Ztschr. 145:154-167, 1924. 9. Dresel, K.: Über das Wesen der oxydationssteigernden Wirkung des Thyroxins , Klin. Wchnschr. 7:504-505 ( (March 11) ) 1928.Crossref 10. McEachern, D.: Direct Measurements of Oxygen Consumption of Isolated, Beating Auricles from Normal and Thyrotoxic Guinea-pigs , Bull. Johns Hopkins Hosp. 50:287-296 ( (April) ) 1932. 11. McEachern, D.: Metabolism of Isolated Surviving Tissues from Animals Rendered Hyperthyroid with Thyroxine , Bull. Johns Hopkins Hosp. 56:145-179 ( (March) ) 1935. 12. Gordon, E. S., and Heming, A. E.: Effect of Thyroid Treatment on Respiration of Various Rat Tissues , Endocrinology 34:353-360 ( (June) ) 1954.Crossref 13. Lewis, J. K., and McEachern, D.: Persistence of Accelerated Rate in Isolated Hearts of Thyrotoxic Rabbits: Response to Iodides, Thyroxine and Epinephrine , Bull. Johns Hopkins Hosp. 48:228-241 ( (April) ) 1931. 14. Aub, J. C., and Stern, N. S.: Influence of Large Doses of Thyroid Extract on Total Metabolism and Heart in Case of Heart Block , Arch. Int. Med. 21:130-138, 1918.Crossref 15. Bing, R. J., and others: Measurement of Coronary Blood Flow, Oxygen Consumption, and Efficiency of Left Ventricle in Man , Am. Heart J. 38:1-24 ( (July) ) 1949.Crossref 16. Rowe, G. G., and others: Hemodynamics of Thyrotoxicosis in Man with Special Reference to Coronary Blood Flow and Myocardial Oxygen Metabolism , J. Clin. Invest. 35:272-276 ( (March) ) 1956.Crossref 17. Ullrick, W. C., and Whitehorn, W. V.: Influence of Thyroid Hormone on Respiration of Cardiac Tissue , Am. J. Physiol. 171:407-411 ( (Nov.) ) 1952. 18. Barker, S. B., and Klitgaard, H. M.: Metabolism of Tissues Excised from Thyroxine-Injected Rats , Am. J. Physiol. 170:81-86 ( (July) ) 1952. 19. Stead, E. A., Jr., and others: Studies on Cardiac Output and of Blood Flow and Metabolism of Splanchnic Area, Brain, and Kidney , Tr. A. Am. Physicians 63:241-245, 1950. 20. Sokoloff, L.; Wechsler, R. L.; Balls, K., and Kety, S.: Relation of Cerebral O2 Consumption to Total Body Metabolism in Hyperthyroidism , J. Clin. Invest. 29:847 ( (June) ) 1950. 21. Myers, J. D.; Brannon, E. S., and Holland, B. C.: Correlative Study of Cardiac Output and Hepatic Circulation in Hyperthyroidism , J. Clin. Invest. 29:1069-1077 ( (Aug.) ) 1950.Crossref 22. Lardy, H. A., and Feldott, G.: Metabolic Effects of Thyroxine in Vitro , Ann. New York Acad. Sc. 54:636-648 ( (Dec. 28) ) 1951.Crossref 23. Hamilton, W. F.: Lewis A. Conner Memorial Lecture: Physiology of Cardiac Output , Circulation 8:527-543 ( (Oct.) ) 1953.Crossref 24. Ellis, L. B., and others: Effect of Myxedema on Cardiovascular System , Am. Heart J. 43:341-356 ( (March) ) 1952.Crossref
TI - Effect of Thyroid Hormone on Circulation
JF - A.M.A. Archives of Internal Medicine
DO - 10.1001/archinte.1957.00260020001001
DA - 1957-02-01
UR - https://www.deepdyve.com/lp/american-medical-association/effect-of-thyroid-hormone-on-circulation-8DUjbiYsYc
SP - 165
EP - 171
VL - 99
IS - 2
DP - DeepDyve
ER -