TY - JOUR
AU - Liu, Bi‐Feng
AB - Microfluidic chip electrophoresis has been widely employed for separation of various biochemical species owing to its advantages of low sample consumption, low cost, fast analysis, high throughput, and integration capability. In this article, we reviewed the development of four different modes of microfluidics‐based electrophoresis technologies including capillary electrophoresis, gel electrophoresis, dielectrophoresis, and field (electric) flow fractionation. Coupling detection schemes on microfluidic electrophoresis platform were also reviewed such as optical, electrochemical, and mass spectrometry method. We further discussed the innovative applications of microfluidic electrophoresis for biomacromolecules (nucleic acids and proteins), biochemical small molecules (amino acids, metabolites, ions, etc.), and bioparticles (cells and pathogens) analysis. The future direction of microfluidic chip electrophoresis was predicted.
TI - Microfluidic chip electrophoresis for biochemical analysis
JF - Journal of Separation Science
DO - 10.1002/jssc.201900758
DA - 2020-01-01
UR - https://www.deepdyve.com/lp/wiley/microfluidic-chip-electrophoresis-for-biochemical-analysis-8BiDxr29vM
SP - 258
EP - 270
VL - 43
IS - 1
DP - DeepDyve
ER -