TY - JOUR AU - Wheelis, Susan AB - Support Care Cancer (2017) 25:1853–1858 DOI 10.1007/s00520-017-3570-6 ORIGINAL ARTICLE Impact of recommended weight-based dosing of granulocyte-colony stimulating factors in acute leukemia and stem cell transplant patients 1 1 1 2 Jennifer K. Hockings & Diwura K. Owolabi & Joyce E. Broyles & Susan C. Wheelis Received: 2 September 2016 /Accepted: 9 January 2017 /Published online: 25 January 2017 Springer-Verlag Berlin Heidelberg 2017 Abstract 5 mcg/kg, the recommended 5 mcg/kg or over 5 mcg/kg G- Purpose Febrile neutropenia (FN) is a major risk factor for CSF (10.1 ± 6.7 days, 8.9 ± 9.2 days, 10.1 ± 9.1 days, respec- infection-related morbidity and mortality. The National tively). Length of stay was similar for patients regardless of Comprehensive Cancer Network recommends the prophylac- initial G-CSF dose (29.6 ± 16.0 days, 29.1 ± 18.4 days, and tic use of granulocyte-colony stimulating factors (G-CSF), 24.5 ± 17.0, respectively). However, the incidence of FN was dosed at 5 mcg/kg and rounded to the nearest vial size. A significantly greater for those who received under 5 mcg/kg of previous medication use evaluation conducted within a G-CSF (87% for under, 68% for recommended, and 54% for multi-hospital healthcare system demonstrated that only 67% over). of patients were TI - Impact of recommended weight-based dosing of granulocyte-colony stimulating factors in acute leukemia and stem cell transplant patients JF - Supportive Care in Cancer DO - 10.1007/s00520-017-3570-6 DA - 2017-01-25 UR - https://www.deepdyve.com/lp/springer-journals/impact-of-recommended-weight-based-dosing-of-granulocyte-colony-7lAdKLlBLQ SP - 1853 EP - 1858 VL - 25 IS - 6 DP - DeepDyve ER -