TY - JOUR
AU - Huber, Kurt
AB - Clin Res Cardiol (2012) 101:305–312 DOI 10.1007/s00392-011-0393-1 OR IGINAL PAPER Efficacy and safety of a high loading dose of clopidogrel administered prehospitally to improve primary percutaneous coronary intervention in acute myocardial infarction: the randomized CIPAMI trial • • • • Uwe Zeymer Hans-Richard Arntz Bernd Mark Stephan Fichtlscherer • • • • Gerald Werner Ralph Scho ¨ ller Ralf Zahn Frank Diller • • Harald Darius Thorsten Dill Kurt Huber Received: 9 August 2011 / Accepted: 29 November 2011 / Published online: 21 December 2011 Springer-Verlag 2011 Abstract for primary PCI has not been studied in prospective ran- Objectives To compare a loading dose of 600 mg clopi- domized trials. dogrel given in the prehospital phase versus clopidogrel Methods The primary efficacy endpoint was the TIMI 2/3 administered only after the diagnostic angiogram in patency of the infarct-related artery in the diagnostic patients with STEMI scheduled for primary PCI. angiography immediately prior to PCI. Background The optimal time and dose for the initiation Results We randomized 337 patients to prehospital of clopidogrel therapy in patients with STEMI scheduled (n = 166) loading dose versus standard therapy (n = 171). The time interval between initiation of clopidogrel therapy and diagnostic 
TI - Efficacy and safety of a high loading dose of clopidogrel administered prehospitally to improve primary percutaneous coronary intervention in acute myocardial infarction: the randomized CIPAMI trial
JF - Zeitschrift für Kardiologie
DO - 10.1007/s00392-011-0393-1
DA - 2011-12-21
UR - https://www.deepdyve.com/lp/springer-journals/efficacy-and-safety-of-a-high-loading-dose-of-clopidogrel-administered-7jqIbIGjG4
SP - 305
EP - 312
VL - 101
IS - 4
DP - DeepDyve
ER -