TY - JOUR
AU1 - Eskilsson, Eskil
AU2 - Verhaak, Roel G. W.
AB - Neuro-Oncology Neuro-Oncology 18(8), 1037–1039, 2016 doi:10.1093/neuonc/now064 Advance Access date 28 May 2016 Longitudinal genomic characterization of brain tumors for identification of therapeutic vulnerabilities Eskil Eskilsson and Roel G. W. Verhaak Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas (E.E., R.G.W.V.); Department of Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center, Houston, Texas (R.G.W.V.) Corresponding Author: Roel G. W. Verhaak, PhD, Department of Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030 (rverhaak@mdanderson.org). Tumor recurrence presents substantial clinical challenges and is (reminiscent of our deviant tumor pairs) and further revealed a leading cause of cancer mortality. Comprehensive genomic that epigenetic and genomic events converge during malignant profiling initiatives, including the coordinated efforts of The progression. Epigenetics are broadly implicated in cancer, and Cancer Genome Atlas (TCGA), have enabled the identification incriminating epigenetic events in malignant progression of gli- and cataloging of genomic alterations across the primary oma add another dimension to the model in which progression tumor ofall major cancers;yet,these tumors,including the is largely driven by genetic alterations. A fifth report, by Bai highly malignant brain tumor glioblastoma (GBM), are not stat- et al., 
TI - Longitudinal genomic characterization of brain tumors for identification of therapeutic vulnerabilities
JF - Neuro-Oncology
DO - 10.1093/neuonc/now064
DA - 2016-08-01
UR - https://www.deepdyve.com/lp/oxford-university-press/longitudinal-genomic-characterization-of-brain-tumors-for-7cNLUg0FzJ
SP - 1037
EP - 1039
VL - 18
IS - 8
DP - DeepDyve
ER -