TY - JOUR
AU - INOUE,, Keizo
AB - Abstract An extracellular phospholipase A2 was detected in the peritoneal cavity of rats injected intraperitoneally with casein. This activity required Ca2+ ion and had a pH optimum of 9. The increase of phospholipase A2 activity in the peritoneal fluid as a function of time roughly paralleled the increase in the number of polymorphonuclear (PMN) leukocytes found in the peritoneal cavity. Phospholipase A2 activity was also observed in rat PMN homogenates, and its characteristics were similar to those of the enzyme found in cell-tree peritoneal fluid fraction. PMN leukocytes may release non-lysozomal phospholipase A2 into the extracellular space as ‘inflammation reactions’ proceed. This content is only available as a PDF. Author notes 1 This work was supported in part by Grant-in-Aid for Scientific Research (No. 60106007) from the Ministry of Education, Science and Culture of Japan. Copyright © 1986, by the Japanese Biochemical Society
TI - Extracellular Phospholipase A2 Activity in Peritoneal Cavity of Casein-Treated Rats
JF - The Journal of Biochemistry
DO - 10.1093/oxfordjournals.jbchem.a121791
DA - 1986-10-01
UR - https://www.deepdyve.com/lp/oxford-university-press/extracellular-phospholipase-a2-activity-in-peritoneal-cavity-of-casein-7avQtcwRFs
SP - 1099
EP - 1101
VL - 100
IS - 4
DP - DeepDyve
ER -