TY - JOUR AU - LIDDELL, J. AB - PSEUDO-CHOLJNESTERASE H. Lehmann, E. Silk & J. Uddell spleen (Banister, Whittaker & Wijcsundera, 1951), inhibits true cholinesterase and is broken down by pseudo- cholinesterase. PSEUDO-CHOT JNFSTKRASE Pseudo-cholinesterase can be estimated by a method in which hydrolysis of acctylcholine in a bicarbonate buffer produces carbon dioxide, which is then measured mano- H. T.FHMANN MD. Sc.D. M.R.C.P. F.R.I.C. metricflliy. The micromanometer used is the Warburg E. SH K M.Sc. apparatus. One unit of pseudo-cholinesterase is defined as that amount of enzyme which produces the evolution of one Department of Pathology St Bartholomew's Hospital, London microlitre of carbon dioxide in one minute at 37° C. (McArdle, 1940). The normal range is 55-125 units/ml. The plasma enzyme is formed in the liver, and its level is reduced by liver 3. T.TDDELL M.B. B.Chir. cell damage. The estimation of plasma pseudo-cholinesterase Nuffield Department of CIMcal Biochemistry has therefore proved a relatively sensitive test of liver function. Padcliffe Infirmary, Oxford Plasma levels may also be markedly depressed in malnutri- tion, cachexia, and in poisoning by organo-phosphorus 1 Cholinesterases compounds, which include the "nerve gases" and many 2 Suxnmethonium modern insecticides. 3 Inheritance of low plarnia pseudo-cholinesterase activity 4 Atypical pseudo-cholinesterase 5 Population surveys 6 Mode TI - PSEUDO-CHOLINESTERASE JO - British Medical Bulletin DO - 10.1093/oxfordjournals.bmb.a069914 DA - 1961-09-01 UR - https://www.deepdyve.com/lp/oxford-university-press/pseudo-cholinesterase-73Bl9ga8GS SP - 230 EP - 233 VL - 17 IS - 3 DP - DeepDyve ER -