TY - JOUR AU - Harshman, Lyndsay AB - Purpose of review This review discusses the complications of nutrition, growth, neurocognitive function, and mineral and bone disorder in pediatric chronic kidney disease. We discuss the most recent evidence-based methods for evaluation and preven- tion of these complications in addition to treatment strategies to address the complica- tions and mitigate adverse effects. Recent findings Frequent nutritional assessment is important, particularly for infants and young children. Due to anorexia, oral aversion, and dietary restrictions, weight gain may be difficult to achieve. Adequate nutrition is important for growth. Children with CKD tend to be short, which can impact quality of life and social achievements. Once nutrition is optimized, growth hormone is an effective, but underutilized strategy to improving terminal height. Mineral and bone disorder is a difficult but common complication of CKD which may present with and be driven by abnormalities in calcium, phosphorus, and parathyroid hormone levels. Treatment strategies include dietary phosphorus restriction, phosphorus binders, and inactive vitamin D and active vitamin D sterols. Effective treatment may reduce the risk for bone deformities, growth abnormalities, fractures, cardiovascular disease, and mortality. Children with CKD also suffer from cognitive Chronic Kidney Disease: Treatment of Comorbidities I Kogon and Harshman 79 difficulties. Control TI - Chronic Kidney Disease: Treatment of Comorbidities I (Nutrition, Growth, Neurocognitive Function, and Mineral Bone Disease) JF - Current Treatment Options in Pediatrics DO - 10.1007/s40746-019-00152-9 DA - 2019-04-15 UR - https://www.deepdyve.com/lp/springer-journals/chronic-kidney-disease-treatment-of-comorbidities-i-nutrition-growth-6kvB5CvLig SP - 78 EP - 92 VL - 5 IS - 2 DP - DeepDyve ER -