TY - JOUR AU1 - Cetin, Irene AU2 - Pardi, Giorgio AB - Introduction Intrauterine growth relies on the supply of nutrients from the mother to the fetus through the placenta. Amino acids represent the main source of nitrogen for the growing fetus. In the normal fetal lamb the uptake of amino acids from the umbilical circulation through the placenta far exceeds the rate of nitrogen accretion, consistent with studies that have shown a fairly high rate of amino acid catabolism and oxidation in the fetus (1). In animals during maternal starvation the fetal oxidation of aminoacids can increase äs in the case of leucine from 17 to 35% of the leucine fetal disposal rate (2). Recently, the availability of techniques to sample fetal blood in utero (3), has made possible the study of features of placental transport and fetal metabolism throughout gestation. The diagnostic value of blood sampling in fetuses with intrauterine growth retardation (IUGR) has been discussed recently (4) and the assessment of fetal oxygenation and acid-base balance has proved of aid in determining the optimal time of delivery. Moreover, this approach has provided considerable Knowledge on the metabolic state of the growth retarded fetus that can be compared to similar data in experimental animals. Normal pregnancies In normal TI - FETAL METABOLISM OF AMINO ACIDS JF - Journal of Perinatal Medicine DO - 10.1515/jpme.1994.22.s1.35 DA - 1994-01-01 UR - https://www.deepdyve.com/lp/de-gruyter/fetal-metabolism-of-amino-acids-67F0FOjvCb SP - 35 EP - 38 VL - 22 IS - s1 DP - DeepDyve ER -