TY - JOUR AB - Medical & Surgical De'twtatology 8:152-154 (2007) THE WORLD LITERATURE 9 2007 Springer Science+Business Media, LLC 7. Surgery; lasers Squamous cell carcinoma of the nail Topical mitomycin C appears to prevent apparatus is often misdiagnosed recurrence in shave-removed keloids OBJECTIVE: To define the different clinical presenta- OBJECTIVE: To determine whether application of mit- tions and the main pathological features and to eval- omycin C to the base of shave-removed keloids would uate the most appropriate surgical management of prevent recurrence. subungual squamous cell carcinoma (SCC). BACKGROUND AND METHODS: Keloid scars are BACKGROUND AND METHODS: Subungual SCC is formed by overactivity of fibroblasts producing colla- rare. Its diagnosis is often missed or delayed because gen and cause significant morbidity both from their ap- the clinical presentation is often atypical and can mimic pearance and symptoms. Existing treatments are often other conditions, such as verruca vulgaris, onychomy- unsatisfactory. Topical mitomycin C is known to inhibit cosis, trauma-induced nail dystrophy, or exostosis. A fibroblast proliferation. Ten patients had all or part of retrospective re,dew was performed of all cases of sub- their keloid shave-removed. After hemostasis, topical ungual SCC seen in the authors' institution over a 5-year mitomycin C was applied for 3 TI - Surgery; lasers JO - Medical and Surgical Dermatology DO - 10.1007/BF03038840 DA - 2009-04-28 UR - https://www.deepdyve.com/lp/springer-journals/surgery-lasers-66aTbwQWRA SP - 152 EP - 154 VL - 8 IS - 3 DP - DeepDyve ER -