TY - JOUR
AU - Brunham, Robert, C.
AB - Abstract Gonococcal infections are frequently recurrent and are sustained in human populations by core groups, composed of very sexually active individuals, that have a high incidence and prevalence of infection. Recent advances in typing of gonococci have documented extreme strain heterogeneity, and epidemiologic studies have shown that gonococci vary widely between different geographic regions, within different population groups in a region, and within a given human population over time. The hypothesis of strain-specific immunity to gonococcal infection explains the diversity, dynamics, and recidivism so well-recognized for this organism. If true, this hypothesis will have some bearing on vaccine development and will suggest alternate strategies for disease control. This content is only available as a PDF. Author notes This work was supported in part by grant no. MA 8720 from the Medical Research Council of Canada. During a portion of the work, Dr. Plummer was the recipient of a fellowship from the Medical Research Council of Canada. We are grateful to Wallis DeWitt of the Sexually Transmitted Disease Laboratory Program (Centers for Disease Control) for serotyping gonococcal isolates and to Leslie Slaney of the University of Manitoba for performing antimicrobial susceptibility tests. Please address requests for reprints to Dr. F. A. Plummer, Department of Medical Microbiology, University of Manitoba, 730 William Avenue, Winnipeg, Manitoba, Canada R3E 0W3. © 1987 by The University of Chicago
TI - Gonococcal Recidivism, Diversity, and Ecology
JF - Clinical Infectious Diseases
DO - 10.1093/clinids/9.4.846
DA - 1987-07-01
UR - https://www.deepdyve.com/lp/oxford-university-press/gonococcal-recidivism-diversity-and-ecology-5krTQrgF83
SP - 846
EP - 850
VL - 9
IS - 4
DP - DeepDyve
ER -