TY - JOUR AU - AB - THE JOURNAL OF BIOLOGICAL CHEMISTRY Vol. 279, No. 10, Issue of March 5, pp. 9409 –9416, 2004 © 2004 by The American Society for Biochemistry and Molecular Biology, Inc. Printed in U.S.A. Activation of Raf/MEK/ERK/cPLA2 Signaling Pathway Is Essential for Chlamydial Acquisition of Host Glycerophospholipids* Received for publication, November 3, 2003, and in revised form, December 3, 2003 Published, JBC Papers in Press, December 15, 2003, DOI 10.1074/jbc.M312008200 Heng Su‡, Grant McClarty§, Feng Dong‡, Grant M. Hatch , Zhixing K. Pan , and Guangming Zhong‡** From the ‡Department of Microbiology and Immunology, University of Texas Health Science Center at San Antonio, San Antonio, Texas 78229, Departments of §Medical Microbiology and Pharmacology and Therapeutics, University of Manitoba, Winnipeg, Manitoba R3E OW3, Canada, and Department of Microbiology and Immunology, Medical College of Ohio, Toledo, Ohio 43614 intermediates (20 –22). Indeed, analysis of chlamydial genome Chlamydiae, a diverse group of obligate intracellular pathogens replicating within cytoplasmic vacuoles of sequences (23–27) has revealed that chlamydiae not only short- eukaryotic cells, are able to acquire lipids from host circuit biosynthetic pathways (22, 28) but also possess many cells. Here we report that activation of the host Raf- novel genes for potentially manipulating host cells TI - Activation of Raf/MEK/ERK/cPLA2 Signaling Pathway Is Essential for Chlamydial Acquisition of Host Glycerophospholipids JF - Journal of Biological Chemistry DO - 10.1074/jbc.m312008200 DA - 2004-03-01 UR - https://www.deepdyve.com/lp/unpaywall/activation-of-raf-mek-erk-cpla2-signaling-pathway-is-essential-for-5hqim02VC5 DP - DeepDyve ER -