TY - JOUR
AU1 - Saito, J. K.
AU2 - McKercher, D. G.
AU3 - Castrucci, G.
AB - ATTENUATION OF THE MYXOMA VIRUS AND USE OF THE LIVING ATTENUATED VIRUS AS AN IMMUNIZING AGENT FOR MYXOMATOSIS J. K. SAITO, D. G. McKERCHER AND G. CASTRUCCI* From the Department of Veterinary Microbiology, University of California School of Veterinary Medicine, Davis, California 95616 Myxomatosis has been studied rela­ virus as an immunizing agent was de­ tively little. However, the etiologic cided against for several reasons-the agent of the disease has been the subject virus fails to immunize consistently, the of intensive and widespread investiga­ resulting immunity is short lived, and tion. Interest in the myxoma virus is the virus produces fibromas at the site largely due to the fact that it provides a of inoculation. Even though these tumor virus model for study and to its tumors regress, they are undesirable in widespread use as a biologic weapon to breeding stock and in rabbits sold as control the wild rabbit population in fryers. Australia. Lack of study of the disease Studies by McKercher (1952) demon­ per se results primarily from its limited strated the futility of vaccinating against the disease with inactivated sporadic occurrence as a geographically myxoma virus preparations, of attempt­ localized infection of a domestic animal that 
TI - Attenuation of the Myxoma Virus and Use of the Living Attenuated Virus as an Immunizing Agent for Myxomatosis
JF - The Journal of Infectious Diseases
DO - 10.1093/infdis/114.5.417
DA - 1964-12-01
UR - https://www.deepdyve.com/lp/oxford-university-press/attenuation-of-the-myxoma-virus-and-use-of-the-living-attenuated-virus-5RLrdUCciR
SP - 417
EP - 428
VL - 114
IS - 5
DP - DeepDyve
ER -