TY - JOUR AU1 - Fischer-Posovszky, Pamela AU2 - Roos, Julian AU3 - Kotnik, Primoz AU4 - Battelino, Tadej AU5 - Inzaghi, Elena AU6 - Nobili, Valerio AU7 - Cianfarani, Stefano AU8 - Wabitsch, Martin AB - Obesity is a major health concern. While some children develop comorbidities such as insulin resistance and low-grade systemic inflammation upon weight gain, others stay metabolically healthy. There is an urgent need for clinically relevant markers with prognostic value related to disease development and intervention success. MicroRNAs (miRNAs) are established biomarkers for several disease states. Herein, we give a brief overview of miRNA biogenesis and function and the potential role of circulating miRNA in the context of pediatric obesity. TI - Functional Significance and Predictive Value of MicroRNAs in Pediatric Obesity: Tiny Molecules with Huge Impact? JF - Hormone Research in Paediatrics DO - 10.1159/000444677 DA - 2016-01-01 UR - https://www.deepdyve.com/lp/karger/functional-significance-and-predictive-value-of-micrornas-in-pediatric-5HjUeOi0Tr SP - 3 EP - 10 VL - 86 IS - 1 DP - DeepDyve ER -