TY - JOUR AU - Liuzzo, Giovanna AB - European Heart Journal (2025) 46, 220–222 https://doi.org/10.1093/eurheartj/ehae680 Weekly Journal Scan Weekly Journal Scan: Using multiomic approaches to uncover multicellular immune programmes in coronary syndromes 1, 1,2 Daniela Pedicino * and Giovanna Liuzzo 1 2 Department of Cardiovascular Medicine, Fondazione Policlinico Universitario A. Gemelli—IRCCS, Largo A. Gemelli 8, Rome 00168, Italy; and Department of Cardiovascular and Pulmonary Sciences, Catholic University School of Medicine, Largo F. Vito 1, Rome 00168, Italy Comment on ‘Multiomic analyses uncover immunological signatures in acute and chronic coronary syndromes’ which was published in Nature Medicine, https://doi.org/10.1038/s41591-024-02953-4. Key points • In this observational study, the authors applied a multiomic factor analysis (MOFA) to data obtained from blood of patients presenting with either acute or chronic coronary syndromes (ACS and CCS) with the aim of characterizing multicellular immune signatures in ischaemic heart disease and relating them to disease state and outcomes. • Blood was analysed from patients presenting at the Cardiology Department of the Munich University Hospital (Munich cohort) with a diag- nosis of the following: (i) ACS, limited to patients with ST-elevation myocardial infarction (STEMI, n = 28); (ii) CCS, represented by patients with a diagnosis based on coronary angiography (lumen reduction of >50%) or coronary computed TI - Weekly Journal Scan: Using multiomic approaches to uncover multicellular immune programmes in coronary syndromes JO - European Heart Journal DO - 10.1093/eurheartj/ehae680 DA - 2024-10-18 UR - https://www.deepdyve.com/lp/oxford-university-press/weekly-journal-scan-using-multiomic-approaches-to-uncover-4tZjV90Nd0 SP - 220 EP - 222 VL - 46 IS - 2 DP - DeepDyve ER -