TY - JOUR AU1 - Sumaya, Ciro Valent AB - THE JOURNAL OF INFECTIOUS DISEASES • VOL. 151, NO.6. JUNE 1985 © 1985 by The University of Chicago. All rights reserved. 0022-1899/85/5106-0002$01.00 PERSPECTIVE Ciro Valent Sumaya From the Department of Pediatrics and Pathology, University of Texas Health Science Center, San Antonio, Texas Epstein-Barr virus (EBV) commonly produces infec­ developed later, usually not until several weeks or a tions in early life [1]. These infections are usually few months after clinical onset of the illness. The asymptomatic or associated with mild nonspecific lack of virus-specific IgM together with the presence manifestations [2, 3]. EBV infections tend to mani­ of stable titers of IgO antibodies to EBV capsid an­ fest as infectious mononucleosis (1M) more in de­ tigen and antibodies to EBV nuclear antigen signi­ veloped areas of the world and when the primary fied an old infection. or initial infection occurs in young adult age groups It was noted early that the sera of patients with [4]. The virus was first found in persistently infected Burkitt's lymphoma and nasopharyngeal carcinoma lymphoblastoid cell lines derived from Burkitt's contained an increased prevalence and titer of anti­ lymphoma [5]. EBV preferentially infects B lympho­ bodies to a broad spectrum of EBV antigens [12]. TI - Serological Testing for Epstein-Barr Virus-Developments In Interpretation JF - The Journal of Infectious Diseases DO - 10.1093/infdis/151.6.984 DA - 1985-06-01 UR - https://www.deepdyve.com/lp/oxford-university-press/serological-testing-for-epstein-barr-virus-developments-in-4c12RawK6e SP - 984 EP - 987 VL - 151 IS - 6 DP - DeepDyve ER -