TY - JOUR AU - Kansal, N. K. AB - Correspondence histopathology of both the PG and erythematous plaques It should be noted that the natural history of syphilis revealed a prominent infiltration of neutrophils and follows that at least 60% of patients with syphilis ‘live massive destruction and damage to the epidermis. The and die’ without developing serious complications of the previously reported case also showed similar histopatho- infection even without treatment and, therefore, to logical findings. The association may imply a possible role emphasize, they do not die of syphilis. As is also well for an aberrant regulation of neutrophils in the pathogen- known, many antibiotics are treponemicidal, and use for esis of both SAPHO syndrome and skin lesions like those other concomitant infections is known to abort or modify 5 2 of our patient. the natural course of syphilis. Even so, syphilis has recently been referred to as a ‘lost opportunity 100 years This case is a rare and unusual case of neutrophilic 3,4 later’. Owing to the varied manifestations, it is likely dermatoses, and highlights the association between that the psoriasiform rash of (secondary) syphilis, the SAPHO syndrome and PG. ‘great imitator’, may be missed in a sizeable number of 1 1 1 2 Y. TI - Syphilis screening before initiation of immunosuppressive and biologic therapy for psoriasis and psoriatic arthritis JO - Clinical and Experimental Dermatology DO - 10.1111/ced.13625 DA - 2018-10-01 UR - https://www.deepdyve.com/lp/oxford-university-press/syphilis-screening-before-initiation-of-immunosuppressive-and-biologic-4YEZ2Cy0Gm SP - 831 EP - 831 VL - 43 IS - 7 DP - DeepDyve ER -