TY - JOUR
AU - Osato, Toyoro
AB - Nuclear antigen (EBNA) inducibility by Epstein-Barr virus (EBV) was assessed in relation to the presence of complement (C3) receptors and surface immunoglobulins (SIg) on leukemic lymphocytes. When erythrocyte-antibody-complement complex(EAC)-positive, SIg-negative B cells were exposed to EBV, EBNA synthesis occurred with a high frequency. In contrast, no significant EBNA induction was evident in SIg-positive, EAC-negative B cells. Cells possessing both markers were EBV-infectable, in proportion to the frequency of EAC-rosette formation. These data seem to indicate that EBV susceptibility of human B cells is closely related to the presence of C3 receptors but not SIg. Leukemic T cells and myelogenous leukemia cells were not EBV-susceptible, although some cells were significantly positive for C3 receptors.
TI - Epstein-Barr Virus Susceptibility of B Cells Correlates to the Presence of Complement Receptors but not Surface Immunoglobulins
JF - Intervirology
DO - 10.1159/000149256
DA - 2008-01-01
UR - https://www.deepdyve.com/lp/karger/epstein-barr-virus-susceptibility-of-b-cells-correlates-to-the-4ORbpTLbCc
SP - 118
EP - 122
VL - 16
IS - 2
DP - DeepDyve
ER -