TY - JOUR AU - Millichap, J. Gordon AB - 1 OCTOBER Correspondence several mechanisms, which include the 89%. Lumbar punctures were performed Empiric Use of Antibiotics for Treatment of Respiratory degree of fever, an abnormal immune re- in 14 (14%) of the 100 children, and only Infection and Febrile Seizures 4 of these 14 were12 months of age; all sponse to infection, a neurotropic organ- 14 were negative for bacterial or viral ism, and an elevated cytokine response To the Editor—The article by Dagan meningitis. The majority (78.6%) of pa- [4]. The systemic cytokine responses in et al. [1] and the editorial by Friedman tients with lumbar puncture had complex some patients with influenza-associated and Whitney [2] stress the need for a febrile seizures [5]. complex febrile seizures may resemble reduction in the use of antibiotics for The findings in this and previous stud- those with influenza encephalopathy [6]. treatment of acute respiratory-tract ies [9] are evidence of the need for rapid In contrast to frequently associated viral infections. The investigation by Da- viral testing. An early viral diagnosis infections, such as influenza in Asia and gan et al. found a reduction in resistant should lessen both the practice of almost human herpesvirus-6 in the Unites States, otitis TI - Empiric Use of Antibiotics for Treatment of Respiratory Infection and Febrile Seizures JO - Journal of Infectious Diseases DO - 10.1086/591464 DA - 2008-10-01 UR - https://www.deepdyve.com/lp/oxford-university-press/empiric-use-of-antibiotics-for-treatment-of-respiratory-infection-and-3mu09k1Etp SP - 1094 EP - 1095 VL - 198 IS - 7 DP - DeepDyve ER -